Clinical approach to young hypertension


Norlela SUKOR

Endocrine Unit, Department of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Malaysia



Hypertension affects approximately 30% of the population worldwide. It is a serious disease, expensive to treat, and can lead to long-term morbidity and mortality. Young hypertension, defined as hypertension occurring in patients aged 40 or younger, is now seen more frequently. A correct and holistic approach in the evaluation of patients with suspected young hypertension is essential, as the underlying cause is demonstrable in more than half of the cases. Among these causes include primary aldosteronism, phaeochromocytoma, Cushing’s syndrome, renal parenchymal disease and renal artery stenosis. The detection of these causes is important as it provides an opportunity to convert an incurable disease into a potentially curable disease, hence avoiding the long-term sequelae and complications of hypertension.


Keywords: Young hypertension, secondary hypertension, primary aldosteronism, phaeochromocytoma, Cushing’s syndrome


Correspondence author: Norlela SUKOR, Endocrine Unit, Department of Medicine,  Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latif, 56000 Cheras, Kuala Lumpur, Malaysia. Tel: +60391456087, Fax: +60391456679.

E mail:

Brunei Int Med J. 2013; 9 (2): 81-92