A case of nasal NK/T-cell lymphoma.


Shashi GOPALAN and Balwant Singh GENDEH.

Department of ORL-HNS, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Malaysia.



Extranodal NK/T-cell lymphoma (ENKTCL) nasal type is an increasingly recognised entity that is aggressive clinically and has a distinct clinico-pathological features that is associated with the Epstein- Barr virus. It was previously known as lethal midline granuloma which typically cause destruction of the mid face palatal and orbital walls. It can also involve the skin, soft tissue, testes, gastrointestinal and upper respiratory tract. ENKTCL expresses some T-cell associated antigens, most commonly CD2 and CD3e. We report a case of ENKTCL in a 28-year-old Indonesian pregnant female, who was referred for further management the destructive condition.


Keywords: NK cell, neoplasms, lymphoma, pregnancy, T-cell lymphoma


Correspondence author: Shashi GOPALAN, Department of ORL-HNS, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yakoob Latif 56000, Cheras, Kuala Lumpur, Malaysia. Tel: +603-91455555.

E mail: shashigopalan@yahoo.com

 Brunei Int Med J. 2013; 9 (4): 270-273