Effect of weight loss on cardiovascular risk factors among obese individuals in a weight management programme in Brunei Darussalam.


 Zakaria KAMIS 1, Maria MAGPUSAO 1, Norol Ehsan HAMID 1, Norhayati KASSIM 1, Lin NAING 2

1 Health Promotion Centre, Ministry of Health, Brunei Darussalam and 2 Pengiran Anak Puteri Rashidah Sa’adatul Bolkiah Institute of Health Science, Universiti of Brunei Darussalam, Brunei Darussalam



Introduction: The prevalence of obesity is escalating in Brunei Darussalam with a number of clinics and programme expanding to counteract this problem. Studies have showed that lifestyle intervention with weight loss reduces the risk of cardiovascular (CV) disease. The purpose of the study was to evaluate the outcomes of a Weight Management Programme (WMP), and to examine the correlation between weight change and changes in glycaemic control, blood pressure (BP) and lipid levels. Materials and Methods: A retrospective data collection from obese participants enrolled in a 24-week WMP in 2011. The multidisciplinary programme included educational group sessions, individual counseling and physical exercise classes. Body weight, fasting blood sugar (FBS), BP and lipid profile at baseline and 24-week were retrieved. Results: Obese participants (n=220) enrolled in the programme with 104 (47.3%) completed at 24-week. The mean weight lost was 5.35 kg (6.1%) (p<0.001). Significant reduction in mean FBS (0.31 mmol/l, p=0.009), diastolic BP (2.82 mmHg, p=0.012), and triglyceride, 0.17 mmol/l (p=0.002) and a significant increase in mean high density lipoprotein cholesterol, 0.04 mmol/l (p=0.016) were observed at 24-week. No significant association was found between body weight loss and improvements in the cardiovascular risk factors. Conclusions: Participants who completed a 24-week WMP can significantly and clinically reduce body weight and improve a number of cardiovascular risk factors. The improvements in the risk factors, however, were not associated with the weight loss.


Keywords: Cardiovascular risk factors, diet, lifestyle programme, obesity, physical exercise, weight loss


Correspondence author: Zakaria KAMIS, Health Promotion Centre, Ministry of Health, Commonwealth Drive, Bandar Seri Begawan BB 3910, Brunei Darussalam. Tel: +6732384220 Ext 229

E mail: hjzakaria.hjkamis@moh.gov.bn


Brunei Int Med J. 2014; 10 (1): 10-18