A rare case of Stenotrophomonas maltophilia resistant to Trimethoprim-Sulfamethoxazole (co-trimoxazole)


Terrence Rohan CHINNIAH, Kavitha PRABHU, Norfaridah ISMAIL, Rashidah PPHA AHMAD

Division of Microbiology, Department of Laboratory Services, RIPAS Hospital, Brunei Darussalam




Stenotrophomonas maltophilia (S. maltophilia) is becoming increasingly recognised as an important nosocomial pathogen. Treatment of invasive S. maltophilia infections is difficult due to its intrinsic or acquired resistance to different antibiotics. Trimethoprim-sulfamethoxazole (co-trimoxazole) sensitivity is used as an identification test for S. maltophilia and is recommended as the agent of choice for treatment. But resistance to co-trimoxazole is a serious threat. This report describes the first isolation of S. maltophilia resistant to co-trimoxazole from a patient treated at RIPAS Hospital, Brunei Darussalam.



Keywords: Nosocomial infection, anti-microbial resistance, infections, Xanthomonas maltophilia


Correspondence author: Terrence Rohan CHINNIAH, Division of Microbiology, Department of Laboratory Services RIPAS Hospital, Brunei Darussalam.

Tel; +673 8628914, E mail: trctrc64@gmail.com


Brunei Int Med J. 2014; 10 (4): 212-215