STREPTOCOCCUS PNEUMONIAE HAEMOLYTIC URAEMIC SYNDROME: A CASE REPORT.

Farin MASRA, Sau Wei WONG, Kanaheswari YOGANATHAN, Swee Fong TANG.

Department of Paediatrics, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia.

ABSTRACT

Streptococcus pneumoniae-associated Haemolytic Uraemic Syndrome is a combination of acute haemolytic anaemia, thrombocytopaenia and acute kidney injury in a patient with S. pneumoniae infection. It constitutes 5-15% of all HUS cases while the incidence of HUS following invasive S. pneumoniae infection is estimated at 0.4-0.6%. We describe two paediatric patients aged 16 months and 18 months respectively, who were admitted for Streptococcus pneumoniae pneumonia. They subsequently developed Haemolytic Uraemic Syndrome a few days after admission. Both of the cases required renal replacement therapy. One of them recovered fully with normal renal function while the other progressed to chronic kidney disease. These two cases summarise an uncommon but serious complication and outcome of patients with Streptococcus pneumoniae-associated Haemolytic Uraemic Syndrome.

Keywords: Haemolytic-Uraemic Syndrome, Pneumococcal Pneumonia, Pneumococcal Vaccine, Renal Failure, Streptococcus pneumoniae.

Correspondence: Dr Farin bt Masra, Department of Pediatrics, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latif, 56000 Cheras Kuala Lumpur, Malaysia

Telephone No: 603-91457888; Fax No:603-91456637

Email address: drfarinmasra@gmail.com

Brunei Int Med J. 2018;14:157-160