RHINO-ORBITAL MUCORMYCOSIS IN A POST COVID 19-INFECTED PATIENT: A CASE REPORT AND REVIEW OF LITERATURE.
Nurul Anis MOHD FAUZI1,2, CHUA Hui Heng2,3, Zaleha KAMALUDIN2,3, Sakinah MOHAMAD1,2, Baharudin ABDULLAH1,2, Ramiza Ramza RAMLI1,2, Norasnieda MD SHUKRI1,2
1Department of Otorhinolaryngology-Head & Neck Surgery, School of Medical Sciences, Health Campus, Universiti Sains Malaysia, 16150 Kota Bharu, Kelantan, Malaysia.
2Hospital Universiti Sains Malaysia, 16150 Kota Bharu, Kelantan, Malaysia.
3Department of Pathology, School of Medical Sciences, Health Campus, Universiti Sains Malaysia, 16150 Kota Bharu, Kelantan, Malaysia.
ABSTRACT
Coronavirus disease 2019 (COVID-19), caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-COV 2), was first identified in Wuhan, China, in December 2019 and the outbreak which rapidly spread around the world was officially declared a global pandemic by WHO on March 11, 2020. Covid-19 is associated with bacterial and fungal secondary infection or co-infection but has been inadequately investigated or reported thus far. We present a case of rhino-orbital mucormycosis in a 50-year-old man with multiple comorbidities who was recently infected with COVID-19. He presented with a history of blurring of vision and diplopia of the right eye with right-sided nasal blockage and rhinorrhea. He was treated with intravenous (IV) Amphotericin B, IV Caspofungin and oral Itraconazole and underwent multiple operations for fungal deloading. In this case, we want to emphasize that the clinicians should be aware that the patients with COVID-19 infection who have received steroid therapy may have a high risk of contracting a secondary fungal infection.
Keywords: COVID-19, Fungi, Amphotericin B, Mucormycosis, Surgery.
Correspondence: Dr Norasnieda Md Shukri, Department of Otorhinolaryngology-Head & Neck Surgery, School of Medical Sciences, Health Campus, Universiti Sains Malaysia, 16150 Kota Bharu, Kelantan, Malaysia.
Email address: asnieda@usm.my; Telephone number: +60129002810
Brunei Int Med J.2021;17:109-115