CYSTIC SQUAMOUS METAPLASIA IN A PHYLLODES TUMOUR.

Nurwahyuna ROSLI, Nurismah MD ISA.

Department of Pathology, Faculty of Medicine, Hospital Canselor Tuanku Muhriz, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latif, Bandar Tun Razak, 56000 Cheras, Kuala Lumpur, Malaysia.

ABSTRACT

Phyllodes tumours are uncommon fibroepithelial lesions of the breast characterized by stromal proliferation and overgrowth. The epithelial component may exhibit hyperplastic and metaplastic changes, however, epithelial squamous metaplastic changes forming epidermal cysts are rare occurrences. We report a case of a 56-year-old woman presented with enlarging right breast mass with suspicious clinical and radiological findings. Clinically, she had a huge mobile mass in the right breast with a palpable axillary lymph node. Mammogram revealed a complex mass with BIRADS score 5. She underwent wide local excision. Histopathology revealed benign phyllodes tumour with multiple unremarkable epidermal cysts. Epidermal cysts arising from squamous metaplasia within a phyllodes tumour are rare. It may give rise to indefinite clinical and radiological findings with malignant transformation being a possibility.

Keywords: Breast, Epidermal cyst, Fibroepithelial lesions, Phyllodes tumour, Squamous metaplasia.

Corresponding Author: Nurwahyuna Rosli, Department of Pathology, Faculty of Medicine, Hospital Canselor Tuanku Muhriz, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latif, Bandar Tun Razak, 56000 Cheras, Kuala Lumpur, Malaysia.

Tel: +603-91455355, Fax: +60-391459485

Email: nurwahyuna@ukm.edu.my

Brunei Int Med J.2023;19:54-58