Bioactive Glass S53P4 Alternatives to Autologous Bone Graft in the Management of Large Bone Defects in Children.

 

Mohd Anuar Ramdhan IBRAHIM1, Faris Indra Prahasta DIDI INDRA*1, and Muhammad Lutfi ABDUL RASHID2.

 

1Faculty of Medicine and Health Sciences, Kota Samarahan, Sarawak.

2Faculty of Medicine, Universiti Malaya Medical Centre, Kuala Lumpur, Malaysia.

 

Abstract

Traumatic bone defects in children are rare, occurring immediately post-trauma or secondary to infected non-union. Autologous bone graft is considered the gold standard and is widely used during the second stage of one of the techniques known as the induced membrane technique. Bioactive glass S53P4 has been proven to share similarities with autografts, especially in the formation of new bone. Its ability to provide local control of infection through antibacterial properties sets it apart from other types of synthetic bone grafts. We utilized bioactive glass S53P4 granules alone in the second stage of the induced membrane technique in a child, resulting in a favorable outcome. The use of bioactive glass S53P4 granules proves practical in cases where a substantial amount of bone graft is needed to fill more significant bone defects, thereby avoiding donor site morbidity.

 

Keywords: Autografts, Bioactive glass, Bone defects, Bone grafts, S53P4.

 

Corresponding author: Faris Indra Prahasta DIDI INDRA, Faculty of Medicine and Health Sciences, Kota Samarahan, Sarawak.

Email: prahasta_82@yahoo.com

 

Brunei Int Med J.2024;20:109-113

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